abstract：:Arterioles in various vascular beds have been often observed to have nonuniform diameters along the vessel axis. The effect of nonuniformity of arteriolar diameter on vascular resistance was investigated using a theoretical model of blood flow in arterioles. Viscous flow of a Newtonian fluid in tubes with periodically...

journal_title：Microvascular research

authors： Sugihara-Seki M,Minamiyama M,Hanai S

更新日期：1989-09-01 00:00:00

abstract：:Capillaries are often assumed to be indistensible. Only recently has the error caused by capillary distensibility in the measurement of hydraulic conductance been considered. An oil-drop method was used to measure simultaneously distensibility and hydraulic conductance (Lp) of mesenteric capillaries of 40 cranially pi...

journal_title：Microvascular research

authors： Baldwin AL,Gore RW

更新日期：1989-07-01 00:00:00

abstract：:Studies of blood flow in mesentery, cremaster muscle, and small bore glass tubes were performed to obtain a relationship between mean velocity (Vmean) and red cell velocity using the two-slit method under epifluorescence (Vepi) and transillumination (Vtrans) microscopy. The velocities Vepi and Vtrans obtained in vivo ...

journal_title：Microvascular research

authors： Seki J,Lipowsky HH

更新日期：1989-07-01 00:00:00

abstract：:Microvascular blood flow is commonly calculated from a "centerline" velocity derived from the dual-slit method. This is done by relating the computed centerline velocity to an average velocity through an empirically derived conversion factor. To determine the physical basis of the conversion factor, we utilized a Four...

journal_title：Microvascular research

authors： Lee JS,Duling BR

更新日期：1989-05-01 00:00:00

abstract：:We present a simple method for isolation and long-term cultivation of porcine and murine cerebral capillary endothelial cells (cEC). Two major points are made. First, that the "characteristic" morphology of the endothelial cells depends mainly on the presence of endothelial cell growth factors in the culture medium an...

journal_title：Microvascular research

authors： Tontsch U,Bauer HC

更新日期：1989-03-01 00:00:00

abstract：:Spontaneous contractions and those elicited by electrical stimulation were studied in isolated segments of bovine mesenteric lymphatic vessels. The effects of three general anesthetics, pentobarbitone, halothane, and ether, on these spontaneous and evoked contractions were studied. Pentobarbitone and halothane inhibit...

journal_title：Microvascular research

authors： McHale NG,Thornbury KD

更新日期：1989-01-01 00:00:00

abstract：:Previous studies on mice have revealed that the Griffonia simplicifolia I (GSI) lectin selectively binds to capillaries in a number of microvascular beds. These observations suggest that the lectin might be a suitable microvascular marker for physiological studies of skeletal muscle, particularly when fluorescent visu...

journal_title：Microvascular research

authors： Hansen-Smith FM,Watson L,Lu DY,Goldstein I

更新日期：1988-11-01 00:00:00

abstract：:We have videorecorded spontaneous cyclic contractions of capillary walls which often stopped the flow of blood cells, in spleens of rat and mouse. An inverted microscope and oblique lighting were key elements in obtaining images in which the boundaries of cells composing vessel walls were clearly distinguishable. Usin...

journal_title：Microvascular research

authors： Ragan DM,Schmidt EE,MacDonald IC,Groom AC

更新日期：1988-07-01 00:00:00

abstract：:A study was designed to compare three independent measures of cutaneous blood flow in normal healthy volunteers: xenon-133 washout, helium flux, and laser velocimetry. All measurements were confined to the volar aspect of the forearm. In a large group of subjects we found that helium flux through intact skin changes n...

journal_title：Microvascular research

authors： Neufeld GR,Galante SR,Whang JM,DeVries D,Baumgardner JE,Graves DJ,Quinn JA

更新日期：1988-03-01 00:00:00

abstract：:The fluidity (the inverse of viscosity) of red blood cell (RBC) suspensions in vivo was estimated by means of microcirculatory measurements such as RBC flow velocity, micropressure in arterioles and venules, and vessel geometry, and by means of simultaneous macrocirculatory measurements such as volume flow and perfusi...

journal_title：Microvascular research

authors： Driessen G,Scheidt H,Inhoffen W,Sobota A,Malotta H,Schmid-Schönbein H

更新日期：1988-01-01 00:00:00

abstract：:The effect of hemodilution on oxygen delivery to the tissue was investigated analytically by taking into consideration the oxygen loss that occurs along the arterial microvasculature due to diffusion into the tissue and shunting to parallel running venules. The theoretical findings were related to experimental data on...

journal_title：Microvascular research

authors： Mirhashemi S,Ertefai S,Messmer K,Intaglietta M

更新日期：1987-11-01 00:00:00

abstract：:We have performed a mathematical simulation on a CYBER computer of the release, diffusion, and consumption of oxygen in the capillaries and surrounding tissue of peripheral nerve under steady-state conditions. The Krogh-Erlang equation was used to calculate oxygen tension in tissue, while numerical solution of the dif...

journal_title：Microvascular research

authors： Lagerlund TD,Low PA

更新日期：1987-09-01 00:00:00

abstract：:The anatomic arrangement, pressure distribution, and resting vascular tone of the feed arteries located upstream from the rat cremaster microcirculation were determined to characterize the sites of the vascular resistance in this macrovessel segment of the cremaster circulation. The cremaster microcirculation and its ...

journal_title：Microvascular research

authors： Meininger GA,Fehr KL,Yates MB

更新日期：1987-01-01 00:00:00

abstract：:The maturational changes in tissue water spaces and in the fractional exclusion of albumin from the interstitial gel were studied in the developing rabbit using multiple radioactive tracers. Total tissue water and extracellular water decrease with age in all organs studied. Intracellular water decreases in the heart a...

journal_title：Microvascular research

authors： Kwong MS,Egan EA,Ferguson W

更新日期：1986-05-01 00:00:00

abstract：:A microvascular network model described in the preceding paper (B. Dawant, M. Levin, and A. S. Popel, 1986, Microvasc. Res. 31, 203-222) featuring random distribution of vessel diameters and lengths, is extended to calculate the distributions of red blood cell flux and discharge hematocrit throughout the network. A re...

journal_title：Microvascular research

authors： Levin M,Dawant B,Popel AS

更新日期：1986-03-01 00:00:00

abstract：:An intravital microscopic method for quantitative measurement of interstitial concentrations of fluorescent tracers has been applied to the investigation of microvascular permeability in the hamster cheek pouch. Some nanoliters of FITC-dextran mean mol wt (Mw) 20,000, 3000, or sodium fluorescein (Mw 376) were injected...

journal_title：Microvascular research

authors： Ley K,Arfors KE

更新日期：1986-01-01 00:00:00

abstract：:To compute two parameters of capillary protein transport of reflection coefficient (sigma) and permeability--surface area product (PS), two major methods have been employed. The first, or crosspoint method, uses two sets of lymph flow (Jv) and lymph/plasma protein concentration ratios (R) and solves the irreversible t...

journal_title：Microvascular research

authors： Katz MA

更新日期：1985-09-01 00:00:00

abstract：:The purpose of this study was to investigate reactive hyperemia in the capillary network of human skin in terms of the flow per capillary and the density of flow-active capillaries. Seventeen male subjects 20 to 40 years of age were seated with their right foot placed on the stage of a Leitz epi-ilumination microscope...

journal_title：Microvascular research

authors： Richardson D,Schwartz R,Hyde G

更新日期：1985-07-01 00:00:00

abstract：:Oxygen pressure histograms were determined with the multiwire surface electrode from the gastrocnemius muscle in patients with arterial occlusive disease and compared with those of healthy volunteers. Seven out of 22 patients had normally distributed histograms like volunteers, but the mean PO2 values were lower than ...

journal_title：Microvascular research

authors： Creutzig A,Wrabetz W,Lux M,Alexander K

更新日期：1985-05-01 00:00:00

abstract：:The multiple pore model of T. R. Harris and R. J. Roselli (1981, J. Appl. Physiol: Respir. Environ. Exercise Physiol. 50, 1-14), was used to simulate lung lymph flow and protein transport at various levels of microvascular pressure. Response of the three-pore structure determined in that study was found to be in excel...

journal_title：Microvascular research

authors： Roselli RJ,Parker RE,Harris TR

更新日期：1985-05-01 00:00:00

abstract：:The object of the present study was to employ specific pharmacological agents and the chemical sympatholytic drug 6-hydroxydopamine (6-OHDA) to characterize the neural and adrenergic control of vascular smooth muscle tone in arterioles of the hamster cheek pouch. Arteriolar diameters were measured in the superfused ch...

journal_title：Microvascular research

authors： Lombard JH,Chenoweth JL,Stekiel WJ

更新日期：1985-01-01 00:00:00

abstract：:The distribution of anionic sites in the basal laminae of the blood capillaries of the murine pancreas was studied in specimens fixed in ruthenium red (RR)-glutaraldehyde mixtures. The sites appeared as discrete, small (6 to 18 nm) particles distributed throughout the three laminae but concentrated primarily in the la...

journal_title：Microvascular research

authors： Simionescu M,Simionescu N,Palade GE

更新日期：1984-11-01 00:00:00

abstract：:The effects of systemic injections of vasoactive substances were studied in the micro-circulation of the hamster skin fold window preparation, which can be observed without anesthesia, exposure, and acute surgical procedures. The effects were characterized by the continuous measurement of the diameter of the arterial ...

journal_title：Microvascular research

authors： Colantuoni A,Bertuglia S,Intaglietta M

更新日期：1984-09-01 00:00:00

abstract：:This study was designed to determine if vascular dysfunction and enhanced norepinephrine sensitivity occurring in early experimental juvenile diabetes (S. M. Mueller, T. M. Mueller, and P. J. Ertel, 1982, Amer. J. Physiol. 243, H139-H144) persist, improve, or worsen in adulthood. Alloxan was administered to rats at 4 ...

journal_title：Microvascular research

authors： Mueller SM

更新日期：1984-07-01 00:00:00

abstract：:The stereomorphological arrangement of skeletal muscle capillaries depends on many factors. Genetic biochemical composition of muscle fibers, age, and training can interfere with the growth of the capillary network. This study is focused on the age effect of chronic reduction of blood flow, as in arterial stenosis, in...

journal_title：Microvascular research

authors： Brotzu G,Carta M,D'Alia G,Diaz G,Montisci R,Savona G

更新日期：1984-05-01 00:00:00

abstract：:Leukocyte margination in the vessels of the microcirculation has been attributed to a flow-dependent interaction with red cells. To determine the extent of this effect, experiments with human blood were done in 100- to 180-micron tubes to detect changes in cell distribution as a function of hematocrit and flow rate. U...

journal_title：Microvascular research

authors： Goldsmith HL,Spain S

更新日期：1984-03-01 00:00:00

abstract：:The effect of isoprenaline infusion (1 gamma/min) on blood flow in the extremities was studied in 15 Raynaud's disease (RD) patients and 9 healthy controls. A highly significant (P less than 0.0005) decrease in blood flow was seen in the RD subjects. It is suggested that an increased presynaptic beta receptor response...

journal_title：Microvascular research

authors： Giovanni B,Giuseppina CM,Susanna F,Roberto M

更新日期：1984-01-01 00:00:00

abstract：:Capillary diameters in sartorius muscle of frogs were measured in vivo by means of a new computer video method, based on the passage of red blood cells (RBCs) through the capillary (C. Ellis, R. Sanfranyos, and A. Groom (1983), Microvasc. Res. 26, 139-150). The distribution of capillary diameters from 21 frogs was rep...

journal_title：Microvascular research

authors： Safranyos RG,Ellis CG,Tyml K,Groom AC

更新日期：1983-09-01 00:00:00

abstract：:The purpose of this study was to examine the distribution and extent of autoregulatory behavior among arterioles in the arcade network of the cat mesentery. We found that 71% of 169 arterioles studied dilated and 63% showed blood flow autoregulation with arterial pressure reduction to 55-60 mm Hg. There appeared to be...

journal_title：Microvascular research

authors： Gannon BJ,Rosenberger SM,Versluis TD,Johnson PC

更新日期：1983-07-01 00:00:00

abstract：:We have applied theories of mass transfer, in laminar and turbulent flow, to red cells in the stopped-flow apparatus in order to estimate the effect of extracellular diffusion boundary layers on the initial rate of O2 uptake. We compared the theoretical predictions with the results of our previous stopped-flow experim...

journal_title：Microvascular research

authors： Huxley VH,Kutchai H

更新日期：1983-07-01 00:00:00

abstract：:Concentration-response curves are often used as indicators of vascular reactivity and receptor sensitivity. Some investigators use ethylenediaminetetraacetate (EDTA) or ascorbic acid (ASC) to prevent catecholamine oxidation but many others do not. This difference may affect estimates of reactivity. We tested the effec...

journal_title：Microvascular research

authors： Maxwell LC,Herlihy JT,Riedel GL

更新日期：1983-07-01 00:00:00

abstract：:We have used ruthenium red, a cationic dye, to detect at the electron microscopic level the presence of anionic sites in various murine basement membranes, with particular emphasis on those of the microvasculature. We have observed anionic sites in all continuous and fenestrated capillaries examined. Terminal lymphati...

journal_title：Microvascular research

authors： Charonis AS,Wissig SL

更新日期：1983-05-01 00:00:00

abstract：:A theoretical model, appropriate for data interpretation, is presented for the transcapillary fluid exchange and associated intraluminal hydrodynamic and solute transport occurring in the microocclusion of single capillaries. This analysis describes the spatial and temporal behavior of the intraluminal flow. A compari...

journal_title：Microvascular research

authors： Blake TR,Gross JF

更新日期：1983-03-01 00:00:00

abstract：:Studies of microvascular geometry made from microscope observations of tissues in vivo or after perfusion with a silastic elastomer or india ink are restricted to a two-dimensional field of view. Microvascular corrosion casts, however, if of sufficient rigidity and structural integrity, can yield three-dimensional inf...

journal_title：Microvascular research

authors： Potter RF,Groom AC

更新日期：1983-01-01 00:00:00